Lilly's New Podcast Series
The Elixir Factor, Lilly’s new podcast hosted by Joe Kim, senior advisor of clinical operations and data registry, explores the factors that inspire bold advances in science, innovation and the resilience required to change history. Tune in to hear how the Lilly research and development (R&D) team collaborates with partners in advocacy, technology, academia and policy to seek cures or solutions for some of the most difficult diseases. There is always a way to get better at what you are doing – simply say "yes" to the next step. Say yes and subscribe today via your preferred podcasting platform:
Clinical trials are essential to the development and testing of new therapies. Developing a clinical trial is an incredibly challenging process that usually involves a lot of different perspectives. The only way to build simpler, more convenient and patient-friendly trials is to include people's real-life experiences at research sites. On this episode, Joe talks to one of our own Lilly experts, Megan Laker, about the patient experience and design innovation hub. Hear what factors inspired Megan to create CoDESIGN. Joe also talks to patient advocate Shane Lee about his experience in the CoDESIGN simulation as a patient living with lupus.
Our purpose here at Lilly is to unite caring with discovery to create medicines that make life better for people around the world. It is often the personal stories and our own experiences that ultimately inspire bold advances in science and innovation. The path to recovery from some of the most difficult diseases, such as cancer, needs to include more than the right medicine or treatment. On this episode, Joe talks to Terri Wingham, founder and CEO of A Fresh Chapter (AFC). Hear what factors encouraged her to start this nonprofit organization, which facilitates life-changing volunteer and leadership experiences to empower people who have been impacted by cancer. Joe also talks to Lilly scientist Scott Hynes and patient advocates Linnea Olson about their participation in AFC's Peru Odyssey program.
Diabetes is a disease that requires management 24 hours a day, seven days a week. People living with diabetes must calculate complex mental math when deciding how much insulin to dose, while also taking into consideration the effects of their exercise, food intake and even stress levels. Digital technology is changing health care, which brings with it the hope of new solutions such as wearables, apps and mobile devices. On this episode, Joe talks to patient advocate and founder of #openAPS, Dana Lewis. Hear what factors motivated her to seek out digital tools to manager her type 1 diabetes and ultimately create an automated DIY closed-loop system. Joe also talks to Marie Schiller, who leads R&D efforts in global product development for Lilly’s Connected Care and Insulins, about the key to finding new and better solutions for diabetes care.
More From Our First Season
Most of us know a person impacted by cancer. Yet while cancer research has been going on for centuries, we still don’t have a cure. Two major advances, targeted therapy and immunotherapy, have led oncologists to the practice of precision medicine. On this episode, Joe talks to T.J. Sharpe, a cancer survivor and patient advocate. Hear what factors led him to research an alternative treatment plan for stage IV melanoma versus a standard treatment plan, which offered him only months to live. Joe also talks with two passionate scientists, former Lilly leader Dr. Levi Garraway and Dr. Kim Blackwell, who leads the way in Lilly's oncology research and development, specifically in the area of precision medicine.
Why is research important and why do people participate? Finding new and improved medicines is only possible with the help of brave people who participate in clinical trials. On this episode, Joe talks with Lilly Stairs, head of growth and partnership at Savvy Cooperative. Hear what factors caused her transformation from ordinary citizen to passionate patient advocate. Joe and Lilly also debunk the myths associated with clinical trials with Lilly’s own Leigh Anne Naas, a patient experience and design innovation community leader.
Alzheimer’s disease is one of the biggest unmet medical needs of our time. Lilly has been committed to Alzheimer’s research for more than 30 years, and continues to remain determined to find solutions for this horrible disease. In 2015, Lilly provided a grant to Academy Award–nominated filmmaker and health care advocate James Keach to make the documentary Turning Point, which granted him access into “the cave” as the Lilly team learned the fate of the Alzheimer’s Expedition 3 study. On this episode, Joe talks with James and Ron DeMattos, Lilly’s chief scientific officer for neurobiologics. Hear what factors inspired the making of Turning Point and the story of the Lilly scientists on the front lines of Alzheimer’s research, capturing both the disappointment and resilience of those working to disrupt the disease.
Caregiving can be one of the most stressful, emotional and physically exhausting jobs there is. Nearly half of all caregivers who provide help to other adults do so for someone living with Alzheimer’s or dementia. The role of the caregiver also goes far beyond basic day-to-day care. They are also the "voice of the patient" and play a very important role in future solutions. On this episode, Joe talks to a full-time Lilly employee and full-time caregiver, Beth Stafford. Hear what factors motivated her to seek the help of Denise Saxman, care consultant at the Alzheimer’s Association, during her caregiving journey. Joe also talks to Denise about ways to help caregivers and the importance of recognizing them as part of the equation in health care, and in drug discovery and development.
Pain is a uniquely complex problem. As many of us know, pain does not discriminate. It’s personal. It’s subjective, and it affects everyone differently. Pain is also an incredibly challenging area to research because of how subjective it can be. Investigational programs for innovative pain treatments have one of the highest clinical-trial failure rates of any major disease state. Now, new advances in digital health may offer scientists the ability to gain more insight on the course of pain. On this episode, Joe talks to Seth Ginsberg, a health policy advocate and entrepreneur. Hear what factors led him to co-found CreakyJoints, the first online patient community for people suffering from arthritis. Joe also talks to one our of own Lilly scientists, Dr. Mark Mintun, about why pain has proven to be such a challenging area to research.
At the root of most research is data. When data have been collected and analyzed in a meaningful and accurate way, they a reused as evidence. Real world evidence, simply defined, is health information collected outside of a randomized clinical trial. On this episode, Joe talks to Erin Moore, a patient advocate and mother of five. When Erin’s son was diagnosed with cystic fibrosis, she considered it her job to learn all that she could about it to offer a more personalized approach to treating him and giving him the best chance at a good health outcome. Hear what factors motivated her to start collecting real world evidence and to continue doing so for almost 10 years. Her resilience is inspiring.
Real world evidence (RWE) is a powerful tool that can be used to provide insights on diseases, medicines, patient populations and health care practices. RWE also plays an important role in drug discovery and is used by the Food and Drug Administration (FDA) and the pharmaceutical industry. A strategic priority of the FDA is to leverage real world evidence to improve regulatory decisions. On this episode, Joe talks to Brande Yaist, senior director of global patient outcomes and real world evidence at Lilly, about why getting it right is so important. Joe also talks to Dr. Adrian Hernandez, vice dean of clinical research at Duke University, about an exciting new initiative with Google called Project Baseline and why he is hopeful that the collection of RWE in this new digital era will allow us to be more forward-thinking about future health problems.
Learn more about Lilly's R&D efforts here.