2024 Year in Review
:00-:07
[Piano music plays in the background.]
[Red Lilly Logo animation appears on screen on a white background.]
[Video shows scenes of the hills and trees of Southern California.]
:08-:29
[Video shows a woman playing piano, then flashes to black and white photos showing her parents’ wedding and her childhood.]
MYRA: I absolutely love music. My family is from Cuba, and they were Cuban immigrants, but I was born in the U.S. And it was a household filled with music. There are so many beautiful Cuban songs that my mother would be singing. It was just a lovely growing-up time.
:30-:48
[A woman stands in her home, holding sheet music, singing in Spanish. We then hear her speaking over the music.]
MYRA: I'm Myra Solano Garcia…
:49-:51
[Myra is speaking to the camera, with colorful windows in the background.]
MYRA: … and I am living with Alzheimer’s disease.
:52-1:03
[Classical piano music plays in the background as a photo of Myra singing on stage appears.]
MYRA: For so many people, they're so afraid of being on stage. But for me, it has always been so natural. I had opportunities …
1:04-1:11
[The music continues, and the video cuts to Myra speaking to the camera. A title appears with Myra Solano Garcia, Living with Alzheimer’s.]
MYRA: … to travel across the country and just enjoy the power of music.
1:12-1:41
[A man sitting at a piano speaks to the camera. A title appears with Shawn Kirchner, Composer, Songwriter and Publisher. The video shows Myra singing a duet at church as he speaks.]
SHAWN: Myra had a really big career back east as a soloist. So when she first arrived, we were so excited, and we worked with her a lot as a featured soloist. But more recently, I remember one choir practice thinking the question she's asking, describing the page number, the measure number, is just not computing. And it didn't make any sense to me. Once we had the diagnosis of Alzheimer's, then I'm like, oh, my gosh. But I mean, all things withstanding, it's just fantastic that we're able to work with her and that she's contributing so much.
1:42-2:13
[Myra sits at a table in her living room, looking through old photos. We see photos fade in and out on screen as she speaks.]
MYRA: This photo is from when I was just hired at the University of LaVerne as a vice president. I looked a lot younger then. I wonder why? The first two years, I felt were very strong years. It was about the third year when things started not feeling right, and I went to different neurologists and they would say, “No, you're fine. You have ADD.”
2:14-2:21
[Myra is speaking to the camera.]
MYRA: And to be honest, I was thrilled, because I really feared that it was going to be Alzheimer's disease.
2:22-2:39
[More photos of Myra.]
MYRA: When I finally got the Alzheimer's diagnosis, I was relieved because I knew that I was still having cognitive problems. A neuropsychiatrist encouraged me to enter a clinical trial, and I'm so very grateful.
2:40-3:03
[Myra is in her home singing “Someone to Watch Over Me.” We see photos of Myra and her husband. We then see Myra driving in the car and running in her neighborhood.]
MYRA: (speaking) My husband takes great care of me. We have a lot of fun on the weekends. We get in the car, and we just go traveling throughout California. Not too long ago, we did a 5K race. I came in second place in my age group.
3:04-3:16
[Myra is speaking to the camera.]
MYRA: While I have Alzheimer's disease, I can no longer do numbers. I have difficulty with names, but I can still sing.
3:17-3:51
[We hear Myra singing “Amazing Grace” while the camera shows an exterior shot of a continuing care center near her home. We then see Myra singing to a person in the memory unit at the center and continuing to sing “Amazing Grace.”]
MYRA: I volunteer at a continuing care organization, singing with the memory unit residents, and I am fully cognizant that I'm going to be following in their paths. But in the meantime, it just brings me joy. You can see that they're confused, but we start singing, and so many of them know all the words. I think that that is the power of music.
3:52-4:03
[Shawn is speaking to the camera. We then see shots of Myra smiling while volunteering in the memory care unit.]
SHAWN: Music, they say lights up so many areas of the brain, and so it makes total sense that Myra feels at home, despite whatever is going on with her diagnosis. Music is with us to the end.
4:04-4:33
[A choir sings as the camera shows the exterior of a church. The video shows Myra singing as part of her church choir.]
MYRA: I'm so grateful I found a church community that really sings to my soul. I love singing and I love bringing music to others. We're all going to go at some point in time. And if I go via Alzheimer's disease, it is what it is.
4:34-4:47
[The video shows Myra looking at old photos, driving, pulling trash cans into her garage, reading while sitting on her couch, and then shows her again speaking to the camera.]
MYRA: Because I can still do things that are important to me … I can drive, I can take care of the house. I can read. I'm going to focus on those, and I'm not going to focus on the things that I can't do. So I'm not afraid.
4:48-4:50
[Myra is on her back porch, looking to the sky, with her garden in the background.]
MYRA: I'm just living life. And loving life.
4:51-4:55
[Music fades out in the background.]
[The Red Lilly logo appears and fades on a white background.]
The Power of Music
Music isn’t just a love for Myra Garcia — it sustains her. Now living with early Alzheimer’s disease, her passion for song keeps her heart full and her life active.
[Music playing.]
[Red Lilly Logo animation appears on screen on a white background.]
[Black-and-white video shows a man walking in gym shoes on a basketball court. Scenes of men playing basketball.]
00:05-00:29
BILL MCCLEERY
It's really interesting when I play basketball because I don't notice the symptoms when I'm on the court. Sometimes I'll limp into the gym and then get on the basketball court and feel totally normal as I'm running around, and then I'll get done playing and I'll limp out of the gym back to my vehicle. So I don't know if that makes that difference, but there's something that kicks in when you're just dribbling the ball, doing the things that you've done all your life to play that.
[Scenes of men playing basketball transition into a man sitting in his living room. The video transitions from black and white to color.]
00:29-00:57
BILL MCCLEERY
It's just really therapeutic for me, and it just makes the disease not even seem like it's there at that moment. My name is Bill. I was diagnosed at age 50 with Parkinson's disease. Playing basketball as my primary therapy. Twice a week, half court with the guys. I'm the only one that has Parkinson's, and I can still fit into that peer group and play basketball with a group of older guys.
00:57-01:06
BILL MCCLEERY
So I fear or have some trepidation about the time coming that I can't do those sorts of things. I was missing some outside shots.
[A man and woman sit in the stands in the gym watching the basketball game.]
01:06-01:07
AMY MCCLEERY
Well I say good game.
01:07-01:20
BILL MCCLEERY
A good game. All right. Thank you very much.
[A man sitting in his living room.]
They say the non-motor symptoms often come long before the motor symptoms. And I would say I did first experience anxiety and fatigue in the years leading up to my diagnosis and thought something was off.
[A woman is sitting in the living room talking. Video shows scenes of the couple walking and talking.]
01:20-01:36
AMY MCCLEERY
We used to walk together. We would walk a couple of miles every night, and then it got to a point where his toes curl. And so we really got to the point we could not work together. Like that was kind of our time. At the end of the day, you know, it was kind of a grieving process of, we can't do this together.
01:37-01:39
AMY MCCLEERY
But then we just started to find like other things that we could do.
01:39-01:45
BILL MCCLEERY
We'll be holding hands and I squeeze a little bit too hard just without meaning to. And she'll be like, ouch. And loosen up a little bit on the hand-holding.
[Video shows scenes of the couple cooking together and eating dinner with their daughter.]
01:45-01:58
AMY MCCLEERY
We were in a doctor's office and we saw someone in the later stages. The older gentleman was in a wheelchair. At some point, maybe that's or maybe that's in our future, I don't know. We'll figure that out when we get there.
[Video of a man using a computer]
01:58-02:08
BILL MCCLEERY
You know, I'd love to think that there's some research happening somewhere that's going to lead to a great breakthrough. And I'm definitely interested in whether genetic science can be the premise of a cure for Parkinson's.
[Video transitions to a man in a blue suit coat being interviewed in an office setting. Scenes of the man working in the lab are shown.]
02:08-02:26
ANDREW ADAMS
With these kinds of progressive diseases where your brain is degrading, we need to actually focus on what's the root cause and address the root cause of those diseases. And that's where genetic medicine comes in, because we don't want to do incremental things where we target symptoms. What we're looking to do here is make transformational medicines.
[Video transitions to a woman in a dark red jacket being interviewed. Video shows scenes of scientists working in a lab.]
02:26-02:50
MICHELLE LYNN HALL
Genetic medicine is basically doing everything that a lot of the medicines have done for years, but very intentionally focusing on treating and curing diseases at their foundational and root level. You come into your health care provider’s office, and we would give you a treatment that would get into your cells, get into the nucleus, and fundamentally correct a pathogenic mutation in your DNA.
02:50-03:04
MICHELLE LYNN HALL
And you would be done. I'm here because I think the most impactful thing I could do as a scientist in my career is create cures and treatments for debilitating neurodegenerative diseases like ALS, like Alzheimer's, like Parkinson's.
[Video transitions to a man on a porch swing talking with his daughter.]
03:04-03:06
HANNAH MCCLEERY
How have you been dealing with all the symptoms and everything?
03:07-03:18
BILL MCCLEERY
I'm pretty good. Take my meds. like, my left hand acts up now and then. But I'm just glad that my left hand on my right. Yeah, that's not my shooting hand playing basketball. Yeah.
03:18-03:20
HANNAH MCCLEERY
To make the three pointers.
[Video transitions to show a man sitting in his living room. Video shows scenes of the man filling up a bird feeder in his yard, and we then see him back on the basketball court.]
03:20-03:45
BILL MCCLEERY
That's right. With three daughters I do look forward to things like being part of their weddings. being part of grandkids someday. I don't think Parkinson's has to be a barrier or an impediment to that. I look to the future and plan on being there and being active and being part of things for years to come. One thing I've told my neurologist is that if she'd like to become famous by becoming the person to cure Parkinson's, I'll volunteer to be the person she cures it in.
03:45-03:54
BILL MCCLEERY
I mean, I do hope there's a cure someday, whether it benefits me or generations down the road. So I'm hopeful. I hope to be able to continue that and to stay positive no matter what.
[Red Lilly logo appears.]
[Music fades in the background.]
Waiting on a Breakthrough
Through advancements in genetic medicines, we’re working to give new hope to people–like Bill — living with Parkinson’s disease.
00:00-00:02
[Music playing.]
[Red Lilly Logo animation appears on screen on a white background.]
00:03-00:16
[A man with a beard, named Edgar, is sitting in his kitchen talking to the camera. He’s wearing black glasses and a long-sleeved denim shirt with a green T-shirt underneath. The video cuts to photos of Edgar smiling as he talks over the pictures.]
Title: EDGAR, DIAGNOSED WITH OBSTRUCTIVE SLEEP APNEA IN 2016
EDGAR: There were moments before I was diagnosed where I would ask myself, "Why am I so tired?" I thought I was just a very sleepy person, that I was not as in shape or fit or athletically active.
00:17-00:35
[Photos show Edgar on vacation in Colorado, dressed in a warm winter coat and ski cap with snow in the background.]
EDGAR: I was diagnosed with sleep apnea as a follow-up to an emergency I had while vacationing in Colorado. The first day I was already feeling very exhausted, very weak, and I thought that perhaps it was getting used to the altitude. I had to be taken to the emergency room in the middle of our vacation.
00:36-00:38
[Photos show Edgar with wires attached to him during a sleep study.]
EDGAR: So when I came back, that's when I had a sleep study done.
00:39-00:46
[Edgar's partner, Frankie, is sitting in their kitchen, talking to the camera. He also has a beard and is wearing red glasses and a light green T-shirt under a white shirt.]
Title: FRANKIE, EDGAR'S PARTNER
FRANKIE: In the middle of the night. I'll hear a (gasping noise). He'll have that one, like gasp of air and it wakes me up because it's so loud and abrupt.
00:47-00:51
[Scenes of the men trying to sleep.]
FRANKIE: When he doesn't get a good night's sleep, he's like a walking zombie. I feel so bad when I see it.
00:52-00:58
[Edgar is talking to the camera. Scenes show Edgar watering plants in their home.]
EDGAR: Making sure that we're getting a proper good night's sleep is important because it affects everything else when you're awake.
00:59-01:07
[Frankie is talking to the camera.]
FRANKIE: When I was learning how he had to sleep with his apnea, I was more curious than anything. Tell me more about this. I want to learn.
01:08-01:12
[Edgar is talking to the camera.]
EDGAR: I have come to appreciate sleep as an activity in my life.
01:13-01:24
[Scenes show Edgar getting ready for bed, sleeping in bed, and talking with Frankie over coffee in the morning.]
EDGAR: We communicate about our sleep. We communicate about our needs. We've been able to talk about, when I go to bed, when he goes to bed, and some of the things that are necessary for us to have a successful night of sleep.
01:25-01:36
[Frankie is speaking to the camera. Scenes show the couple playing video games in their living room.]
FRANKIE: This actually ended up making our relationship stronger because we can talk about our sleep. What else do we need to talk about? We're able to share that, understand, empathize with each other, thus making that relationship even more strong.
01:37-01:40
[Scenes show Frankie and Edgar playing pickleball on a blue and green court in a local park. Edgar is wearing a yellow T-shirt and bright multi-color shorts, while Frankie is wearing a grey shirt and green shorts.]
FRANKIE: We definitely get competitive with pickleball. We really enjoy it.
01:41-01:45
EDGAR: With friends, we meet every week, we play, we've done leagues, which has been really nice.
01:46-01:48
FRANKIE: It's honestly just a good, fun time for us.
01:49-01:58
[Edgar is back sitting in the kitchen, talking to the camera.]
EDGAR: My sleep routine is sacred. I am a force and I am ready to go to bed. And nothing can stop me. It is an event. You don't need a ticket for it. It's kind of nice. It's free.
01:59-02:01
[Scene shows Edgar and Frankie outside their home. Frankie has his arm around Edgar.]
EDGAR: Sleeping is...yeah...I love it.
02:02-02:05
[Red Lilly logo appears.]
[Music fades in the background.]
Living with OSA: Edgar's Story
Like Edgar, many people are unaware of their breathing interruptions during sleep. Working to dispel misconceptions, it’s time to learn more about obstructive sleep apnea.
Additional Resources
Lilly Cautionary and Other Statements
The statements made in the 2024 Year in Review may contain forward-looking statements that are based on management’s current expectations and assumptions, but actual results may differ materially due to various factors. Words such as “estimate”, “project”, “intend”, “expect”, “believe”, “target”, “anticipate”, "may", "could", "aim", "seek", "will", "continue" and similar expressions are intended to identify forward-looking statements. However, by their nature, forward-looking statements are subject to risks, uncertainties and assumptions that are difficult to predict or quantify. You should not place undue reliance on forward-looking statements, which speak only as of the date they are made. Certain important factors that could cause actual results to differ, possibly materially, from expectations or estimates reflected in such forward-looking statements can be found in the “Risk Factors” and “Forward-Looking Statements” sections included in the company’s Annual Report on Form 10-K for the year ended December 31, 2024, and may be further updated by any subsequent Forms 10-Q or 8-K filed with the Securities and Exchange Commission. The company undertakes no duty to update forward-looking statements except as required by applicable law.
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