Lung Cancer icon

In the UK, people with symptoms of lung cancer usually have an urgent chest X-Ray first.1 Separately, screening programmes for people at high risk use low-dose CT scans2, which can find lung cancer earlier and reduce deaths by around 16%3

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Common symptoms of lung cancer can include:4
  • A cough that does not go away
  • Coughing up blood
  • Chest pain
  • Shortness of breath
  • Wheezing
  • Feeling unusually tired (fatigue)
  • Losing weight without trying
  • Chest infections, such as pneumonia, that keep coming back
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Lifestyle

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Smoking is the leading risk factor for lung cancer. Breathing in other people’s smoke (second-hand smoke) can also increase your risk.5
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Home environment

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Exposure to radon gas in the home can increase the risk of developing lung cancer.5
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Work and community

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Longterm exposure to asbestos, cancer‑ causing‑ chemicals, diesel exhaust, or air pollution in the workplace or community can increase lung cancer risk.5
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Medical and family history

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Having had radiation therapy to the chest, or a personal or family history of lung cancer, can increase your risk of developing the disease.5
FIRST
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Imaging tests

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A chest X‑ray is usually the first test. If needed, a CT scan is used to create detailed images of the lungs and check whether the cancer may have spread. Imaging tests alone cannot confirm lung cancer.7
NEXT
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Lab tests

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Blood tests help rule out some of the possible causes of your symptoms, such as a chest infection.7
THEN
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Biopsy

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A biopsy is the only way to confirm lung cancer. A small sample of tissue is taken and examined under a microscope to identify the cancer type.7
FINALLY
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Biomarker testing

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If lung cancer is confirmed, biomarker testing may be used to look for specific changes in the cancer cells. This helps doctors choose treatments that are more likely to work for certain types of lung cancer.7

References

  1. NHS England; RM Partners. National Optimal Lung Cancer Pathway [Internet].London: NHS England; 1 Jan 2024 [accessed 11 Mar 2026]. Available from: https://rmpartners.nhs.uk/wp-content/uploads/2024/09/national-optimal-lung-cancer-pathway_v4_01jan2024.pdf
  2. UK National Screening Committee. Lung cancer: screening recommendation [Internet].London: UK NSC; 2022 [accessed 11 Mar 2026]. Available from: https://view-health-screening-recommendations.service.gov.uk/lung-cancer/
  3. Field JK, Duffy SW, Baldwin DR, et al. Lung cancer mortality reduction by low‑dose CT screening: UKLS randomised trial and international meta‑analysis [Internet]. Lancet Reg Health Eur. 2021 [accessed 11 Mar 2026]. Available from: https://pubmed.ncbi.nlm.nih.gov/34806061/
  4. NHS. Lung cancer: symptoms [Internet]. London: NHS; [accessed 11 Mar 2026]. Available from: https://www.nhs.uk/conditions/lung-cancer/symptoms/
  5. Macmillan Cancer Support. Causes and risk factors of lung cancer [Internet]. London: Macmillan Cancer Support; [accessed 11 Mar 2026]. Available from: https://www.macmillan.org.uk/cancer-information-and-support/lung-cancer/causes-and-risk-factors-of-lung-cancer
  6. Cancer Research UK. Survival for lung cancer [Internet]. London: Cancer Research UK; [accessed 11 Mar 2026]. Available from: https://www.cancerresearchuk.org/about-cancer/lung-cancer/survival
  7. NHS. Lung cancer: diagnosis [Internet]. London: NHS; [accessed 11 Mar 2026]. Available from: https://www.nhs.uk/conditions/lung-cancer/diagnosis/
  8. NHS. Lung cancer: treatment [Internet]. London: NHS; [accessed 11 Mar 2026]. Available from: https://www.nhs.uk/conditions/lung-cancer/treatment/
CMAT-06471 May 2026