Immunology
How often do you stop and think about your immune system? If you live with one of the more than 80 immune-mediated diseases, you probably think about it more than most.
Immune-mediated diseases are chronic and can have a significant impact on a person’s quality of life due to potential physical, emotional and psychological burdens. Today, four to five percent of people in the world live with an immune-mediated disease.
Even with the current treatment options that are available to treat many immune-mediated diseases, there is still a significant unmet need for people living with these diseases. That is why we aspire to deliver innovative medicines that enable breakthrough outcomes to address the unresolved impact of immune-mediated diseases.
Lilly has been able to provide immunology treatments to more than 1.5 million people around the world, but there are many more in need. That’s what motivates us to continue to find the next generation of treatments.
Understanding the Impact of Immune-mediated Diseases
Addressing Health Equity
:00-:03 [Ambient music plays in background] [Red Lilly Logo animation appears on screen on a white background] :03-:26 [A woman sits in a chair with plants and windows behind her. There is an empty chair in the background. She speaks to the camera.] LIZ: I was put on my first diet that I was aware of in sixth grade. [Two photos of Liz as an adolescent appear on screen. In the first photo, she is smiling while holding a rock by a lake. The second photo, she is smiling while standing on a rock with trees behind her.] LIZ: I was going to France as an exchange student and my mom said, Hey, if you lose X amount of weight, you can earn your pocket money while you're there. [Video returns to Liz speaking to the camera in a close-up from the side.] LIZ: It was very confusing and it was very shameful. It wasn't for not being an active kid. [Photo of Liz as a child wearing a blue dress and smiling] [Photo of Liz as a child wearing a soccer uniform and sitting on a soccer ball.] [Photo of Liz as a child wearing a white shirt, holding her hands up high and smiling as she displays a medal around her neck.] [Photo of Liz as a child, smiling and wearing a tiger costume for Halloween.] :26 - :49 LIZ: I played soccer. I spent my days riding bikes around the neighborhood. I did everything that my sister did or friends did, and I was the only one who had a problem. [Video returns to Liz speaking to the camera.] Liz: That was the first experience with “Oh, this is something society says isn't quite right.” My name is Liz Paul and I live with obesity. CAPTION: LIZ’S STORY [Video transitions from Liz on camera to a black screen with the caption.] :51 – 1:21 [Video transitions from black and we see Liz again speaking to the camera.] LIZ: We've been conditioned to say that people who live in larger bodies are lazy, eating too much. They don't exercise. We're given all of these stereotypes. It's just not true. [Video shows Liz walking into her office] LIZ: I am busy from the moment I get up to the time my kids go to bed. [Video shows Liz working in her office, typing on a computer keyboard.] LIZ: I am the Cubmaster from my daughter's Cub Scout pack. [Photo of Liz with her family in Scout uniforms] LIZ: I am the president of the Mankato Kiwanis Club, which does service projects around town. [Video shows Liz conducting a Kiwanis meeting at a local restaurant.] 01:21 – 1:44 [Video shows Liz playing trumpet on stage at her church.] LIZ: I play trumpet in church. When you live in a larger body, you kind of want to hide yourself. But playing trumpet is something that people enjoy, and it's a chance to say, “Look, I can do something. I'm useful.“ [Video returns to Liz speaking to the camera, beginning to tear up as she speaks.] LIZ: Doctors told me that I was the only one who was ever going to fix me and had nothing but shame and blame for me. 01:44- 2:09 [Photo of Liz exercising at the gym.] [Photo of Liz running a 5K race with a woman by her side.] [Photo of Liz and her husband smiling at their wedding. She is holding a bouquet of red flowers.] [Photo of Liz smiling in a dress.] [Photo of Liz taking a photo in the mirror.] LIZ: I have done CrossFit. I have done five K’s. I have gained and lost hundreds of pounds over my adult life. [Video returns to Liz speaking to the camera.] LIZ: I would say my most successful was after my son was born. [Photo of Liz with her son, sitting on a large rock in front of a home.] [Photo of Liz and her son on a tire swing with tress behind them.] LIZ: I lost 80, 100lbs? And it was great and I felt really good. 2:09-2:34 [Video returns to Liz speaking to the camera.] LIZ: And then it stopped working. The actual disease of obesity came back to really bite me. LIZ: I had lost this weight, but it kept creeping back on and on and up. And I said, “Well, apparently I can't do this. Apparently, I am just a failure. I will always be living in a larger body” and kind of gave into the depression of it all. 2:34-2:45 [Video shows Liz walking up to a greet a woman behind a hotel counter and then receive a blue bag as she checks in for a conference.] LIZ: Around this time, I was invited to the Obesity Action Coalition - their “Your Weight Matters” convention. [Video shows scenes of Liz at the convention, listening to a discussion of experts on a stage in a hotel ballroom.] LIZ: Here were professionals, experts in the field who said obesity is a chronic, complex disease caused by all sorts of things [Video returns to Liz speaking to the camera.] 2:45-2:52 LIZ: that can't be cured just by eating less and moving more. Then I'm like, “What is this and why am I just hearing about this now?” [Video shows more scenes of Liz at the convention. We see a man and woman talking as Liz looks through materials on a table and then joins in their conversation.] 2:52-3:03 LIZ: People who live with obesity deserve access to care, bias-free, stigma-free treatments to help them manage their disease. [Video returns to Liz speaking to camera.] 3:03-3:18 [Video shows Liz walking in the woods. She is wearing a green shirt, a red hat and carrying a walking stick.] LIZ: I'm always trying to lose weight and make good choices and try to move my body every day. I try to eat right. I do as much as I can. I don't like to limit myself, but sometimes my body pays for it. 3:18-3:40 [Video returns to Liz speaking to camera] LIZ: Hopefully one day we'll find the tool or the treatment or anything that'll stick. But I know this will be something I'll be living with my whole life, regardless of whether I have lost weight or not. It's hard to to not be a little bit afraid of all of that. I want to see my kids grow up. I want to be there with them, which is why I never stopped trying to lose weight. [Video shows Liz on camera after her hike in the woods, looking up and then looking to the camera.] 3:40-3:43 [Ambient music fades out in background.] [Red Lilly logo appears and fades out on a white background.]
